Optical Manipulation and Its Applications
  1. Optical Manipulation in Biophysics and Biomedicine
    • Single molecule biophysics
    • Cellular mechanics and mechanotransduction
    • Cellular adhesion
    • Laser cellular surgery and photoporation
    • Light activated drugs and probes
    • Cell stretching
    • Optogenetics
    • Optical biomodulation
  2. Optical Manipulation Fundamentals
    • Holographic optical tweezers and beam shaping, adaptive optics techniques
    • Particle dynamics
    • Opto-mechanical cooling
    • Microrheology
    • High force optical tweezers
    • Photophoresis
    • Optical trap modelling and theoretical underpinnings
    • Nanoparticle manipulation
    • Plasmonic manipulation
    • Integrated and near-field optical trapping
  3. Optical Manipulation Applications
    • Non-equilibrium statistical mechanics
    • Nanoscale & quantum sensing
    • Environmental sensing and aerosol analysis
    • Optofluidics/microfluidics
    • Integration with spectroscopic techniques
    • Photo activated molecules and materials
  4. Alternative Manipulation Techniques
    • Magnetic tweezers
    • Electrical manipulation: Electrodynamic balance, dielectrophoresis, etc.
    • Acoustic manipulation and trapping
    • Microfluidic manipulation
    • Optoelectronic Tweezers
    • AFM applied to techniques studied by optical manipulation
Optics and the Brain
  1. Optics in the Human Central Nervous System and Peripheral Nerves
    • Functional near infrared spectroscopy (fNIRS)
    • Diffuse optical spectroscopy and tomography (DOS/DOT)
    • Diffuse Correlation Spectroscopy (DCS)
    • Wearable systems
    • Brain computer interfaces (BCI)
    • Infrasurgical brain optical imaging
    • Fiber-optic probes, spectroscopy and edoscopic imaging
    • Optical modulation of the human central nervous system
    • Retinal neuroscience
    • Speckle contrast
    • Vascular and metabolic modeling
    • Clinical applications
    • Coherence tomography, non-invasive techniques, hyperspectral imaging
  2. Rethinking Scan Patterns and Shaping Light
    • Light sheet microscopy
    • Wavefront engineering
    • Adaptive optics
    • Structured illumination
    • Temporal focusing
    • Non-gaussian beam shaping
    • Holography
    • Combining light sheet micro with microlaser spectro
  3. Structural and Super-Resolution Techniques
    • Resolution improvement techniques
    • Fluorophores design and optimism
    • Use of super-resolution
    • Particle tracking
    • Molecular and biophysical processes
  4. Analyzing Circuitry, Network Function and Information Processing
    • Model systems for network studies
    • Hybrid theoretical-experimental approaches to network analysis
    • Models of network inference
    • Imaging strategies optimized for network analysis
    • Deciphering functions from activity data
    • Multiscale imaging of brain activity
    • Functional microscopy
  5. Optogenetics, Genetic Encoding and Novel Probes
    • ​Optode and electrode hardware for excitation and/or recording​
    • Use of miniatrue microscopes with optogenetics
    • Genetically encoded calcium and voltage inidcators
    • Novel forms of functional contrast
    • New genetic strategies for optogenetics
    • Modeling and overcoming scatter in optogenetics
    • Challenges of scaling up optogenetics to non-human primates
  6. Scattering, Clearing and Wavefront Engineering
    • ​​Advances in light sheet microscopy
    • Novel techniques for in-vitro and in-vitro whole-brain imaging and actuation
    • Zebrafish, Drosophila and similar small organisms
    • Clearing techniques and structural imaging, animal to human
    • Optical data management and analysis strategies
    • Adaptive optics strategies
  7. Brain Physiology and Disease
    • ​​Application of optical spectroscopy and imaging systems to the study of the brain in both health and disease (i.e., Alzheimer's stroke, epilepsy, etc.)
    • Models of brain diseases and optical tools
    • Photothrombosis
    • Optical therapeutics
    • Photodynamic therapy
    • Neuromodulation strategies
  8. Big Data Tools (Collection, Management, Reduction, Analysis)
    • ​​Rapid imaging strategies
    • Serial slices imaging
    • Large field-of-view and space-bandwidth microscopes
    • Compression strategies
    • Data management tools
    • Machine learning
    • Software tools and date formats
    • ML data augmentation; high density datasets
  9. Optical Hybrids​​
    • Photoacoustics / optoacoustics
    • Acousto-optic approaches
    • Acoustic modulation of neural activity
    • Combined optical / PET / CT / MRI
    • Combined electrical/optical
    • Integrated photo acoustic, ultrasound and angiographic tomography (PAUSAT) and photothermal infrared microscopy