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Topic Categories

Topic Categories


Clinical and Translational Biophotonics (Translational)

  1. Preclinical disease research: techniques and applications
    • Molecular contrast agents, probes and reporters
    • Diffuse optical spectroscopy and Imaging methods for small animal models of cancer and other diseases
    • Optical imaging of the cancer microenvironment, processes and pathways
    • Targeted molecular imaging of cancer and quantitative validation methods
    • Bioluminescence techniques and applications to disease research
    • Photoacoustics in disease research
    • Intravital, Raman and multiphoton microscopy for pre-clinical disease research
  2. Intravital microscopy for clinical applications
    • OCT techniques and applications in humans
    • Endomicroscopy
    • FLIM for clinical applications
    • Multimodal microscopy for clinical applications
    • Raman microscopy and endoscopy for clinical applications
    • Micro-elastography and optical biomechanics
    • Skin imaging techniques and applications
  3. Clinical spectroscopy
    • Optical properties of disease
    • Intravital spectroscopy for clinical applications
    • Hyperspectral imaging techniques and applications in medicine
    • Modeling of light propagation and optical properties
  4. Intrasurgical imaging
    • Optical approaches for surgical guidance
    • Intravital optical biopsy
    • Perfusion evaluation
    • Combined contrast agent / imaging approaches
    • Dynamic contrast
    • Digital staining microscopy
    • Applications in neurological surgery
    • Applications in cancer resection
  5. Non-invasive optical imaging for disease applications
    • Tomography approaches for clinical applications
    • Multi-modal imaging (e.g. combined with x-ray, MRI, ultrasound)
    • Photoacoustic techniques and applications in the clinic
  6. Optical therapeutics / theranostics
    • PDT, agents, techniques and applications
    • Thermal ablation
    • Agents for optical therapy
    • Laser surgery
    • Optical dosimetry
  7. Clinical translation: biophotonics in the clinic and beyond
    • Global health
    • Applications in women’s health
    • Applications in ophthalmology
    • Applications in dermatology
    • New contrast agents in the clinic
    • Testing and evaluation of new clinical modalities
    • Machine Learning and AI approaches
    • Challenges and trajectories of clinical translation
    • Skin color bias studies

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Microscopy, Histopathology and Analytics (Microscopy)

  1. Novel technology, devices, methods, models
    • Miniaturized devices
    • Endoscopic devices
    • Computational microscopy
    • Super-resolution microscopy
    • Wearable microscopy
    • Multimodal microscopy
    • Multispectral and hyperspectral microscopy
    • Mutiplexed and hyperplexed imaging
    • Molecular imaging
    • Raman microscopy
    • Phase microscopy
    • Light-sheet microscopy
    • Label-free imaging
    • Fluorescence lifetime imaging
    • Photoacoustic imaging
    • Affordable microscopy devices for low-resource settings
  2. Computational tools/Machine learning/Deep learning/AI
    • Image denoising, restoration and resolution enhancement
    • Image segmentation and tracking (2D, 3D and 4D)
    • Image translation and generation (e.g., Generative Adversarial Networks (GANs), Diffusion Models)
    • Content based Image Retrieval
    • Diagnostic, prognostic and predictive classification algorithms
    • Multimodal deep learning and fusion of multi-modal data
    • Smart microscopy methods (e.g., closed-loop alignment)
    • Data visualization/rendering, mosaicing, annotation and augmentation
    • Digital staining, digital rendering
    • Handling large and multi-dimensional data (e.g., compression, cloud computing)
    • Data anonymization and federated learning
    • FAIR data and analysis solutions
    • User-friendly open-source tools
    • Clinical testing and impact of AI models
  3. Laboratory-based, pre-clinical, translational and commercial biophotonics
    • Diagnostic, theranostic and therapy methods
    • Quantitative approaches for pathology
    • Contrast agents, reporters, probes, molecules
    • Probe delivery and labeling methods
    • Drug delivery and measurement methods
    • Optical clearing methods
    • Tissue expansion microscopy
    • In situ hybridization, spatial transcriptomics, preservation of nucleic acids
    • Optical microscopy of organoids and engineered tissues
    • Immunological studies (tumor microenvironment, inflammation, wound healing)
    • Animal intravital microscopy
    • Human intravital microscopy
    • Bedside imaging – in vivo, ex vivo methods
    • Ex vivo digital/computational pathology
    • Translational challenges: from lab to the clinic

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Optical Coherence Tomography (OCT)

  1. Novel Technology, Devices, Light sources, Methods and Models
    • Adaptive optics
    • High speed imaging
    • High resolution imaging
    • Long range imaging
    • Catheter-based and endoscopic imaging and sensing probes
  2. Multi-Modality
    • Spectroscopy
    • Fluorescence, Raman, Multiphoton imaging
    • Photoacoustics
    • Brillouin
  3. Functional OCT
    • Optoretinography
    • Dynamic OCT
    • Elastography
    • Polarization
    • Doppler and angiography
    • Spectroscopy
    • Contrast agents
  4. Signal and Image Processing
    • Despeckling
    • Segmentation
    • Digital refocusing and image enhancement
    • Machine Learning for image reconstruction and interpretation
  5. Clinical and pre-clinical Applications
    • Ophthalmology
    • Dermatology
    • Intracoronary, pulmonary and endoscopic clinical OCT
    • Surgical guidance and robotics
    • Animal models
    • Ex-vivo and In-vitro biological tissue imaging
    • Diagnostic imaging
  6.  Low Cost, Miniaturized OCT systems
    • OCT applications in the developing world and low resource areas
    • Integrated photonics OCT systems and components
    • Home (self-) diagnostic systems
  7. Big Data Tools (Collection, Management, Reduction, Analysis)
    • Databases
    • Synthetic data
    • Data management tools
    • Machine learning
    • Software tools and data formats
    • Open science

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Optical Tomography and Spectroscopy (OT&S)

  1. Diffuse optics (DOT/DOS, DCT/DCS, NIRS)
    • Covering all salient aspects ranging from algorithms and devices to pre-clinical and clinical applications.
  2. Laser speckle imaging
    • This area covers the use of laser speckles and their statistics for biomedical imaging and monitoring.
  3. Photoacoustic (optoacoustic) tomography and spectroscopy
    • Covering all salient aspects ranging from algorithms and devices to pre-clinical and clinical applications.
  4. Raman spectroscopy & fluorescence imaging
    • This area covers all levels from the physical basis to novel new devices to pre-clinical and clinical applications, including the development and use of exogenous probes.
  5. Future directions and emerging challenges
    • Novel technological developments and emerging pre-clinical and clinical applications covering a wide range of methods. For example, the use of less explored wavelength ranges (e.g., SWIR), effect of skin tone, development of wearables or implantables, new contrasts, artificial intelligence and new measurement techniques. Moreover, discussion of new challenges connected to non-invasive spectroscopy and tomography with proof-of-principle solutions both on experimental and/or theoretical side are encouraged.

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Optics and the Brain (Brain)

  1. Optics in the human central nervous system and peripheral nerves
    • Functional near infrared spectroscopy (fNIRS)
    • Diffuse optical spectroscopy and tomography (DOS/DOT)
    • Diffuse correlation spectroscopy (DCS)
    • Speckle Contrast Optical Spectroscopy (SCOS)
    • Wearable systems
    • Brain computer interfaces (BCI)
    • Intrasurgical brain optical imaging
    • Fiber-optic probes, spectroscopy and endoscopic imaging
    • Optical modulation of the human central nervous system
    • Retinal neuroscience
    • Speckle contrast
    • Vascular, metabolic modeling and imaging
    • Clinical applications
    • Coherence tomography, non-invasive techniques, hyperspectral imaging
  2. Rethinking scan patterns and shaping light
    • Light sheet microscopy
    • Wavefront engineering
    • Adaptive optics
    • Structured illumination
    • Temporal focusing
    • Non-gaussian beam shaping
    • Holography
  3. Structural and super-resolution techniques
    • Resolution improvement techniques
    • Fluorophores design and optimization    
    • Use of super-resolution
    • Particle tracking
    • Molecular and biophysical processes
  4. Analyzing circuitry, network function and information processing
    • Model systems for network studies
    • Hybrid theoretical-experimental approaches to network analysis
    • Models of network inference
    • Imaging strategies optimized for network analysis
    • Deciphering functions from activity data
    • Multiscale imaging of brain activity
    • Functional microscopy
  5. Optogenetics, genetic encoding and novel probes
    • ​Optode and electrode hardware for excitation and/or recording​
    • Use of miniature microscopes with optogenetics
    • Genetically encoded calcium and voltage indicators
    • Novel forms of functional contrast
    • New genetic strategies for optogenetics
    • Modeling and overcoming scatter in optogenetics
    • Challenges of scaling up optogenetics to non-human primates
  6. Scattering, clearing and wavefront engineering
    • ​​Advances in light sheet microscopy
    • Novel techniques for in-vitro whole-brain imaging and actuation
    • Zebrafish, drosophila and similar small organisms
    • Clearing techniques and structural imaging, animal to human
    • Optical data management and analysis strategies
    • Adaptive optics strategies
  7. Brain physiology and disease
    • ​​Application of optical spectroscopy and imaging systems to the study of the brain in both health and disease (i.e., Alzheimer's, stroke, epilepsy, autism etc.)
    • Models of brain diseases and optical tools
    • Photothrombosis
    • Optical therapeutics
    • Photodynamic therapy
    • Neuromodulation strategies
  8. Functional brain imaging & neurodevelopment
    • Resting-state functional connectivity
    • Optical intrinsic signal imaging
    • Cognitive & neurodevelopment
  9. Big data tools (collection, management, reduction, analysis)
    • ​​Rapid imaging strategies
    • Serial slices imaging
    • Large field-of-view and space-bandwidth microscopes
    • Compression strategies
    • Data management tools
    • Machine learning and Artificial Intelligence
    • Software tools and data      formats
    • ML data augmentation; high density datasets
  10. Optical hybrids​​
    • Photoacoustics / optoacoustics
    • Acousto-optic approaches
    • Acoustic modulation of neural activity
    • Combined optical / PET / CT / MRI
    • Combined electrical/optical
    • Integrated photo acoustic, ultrasound and angiographic tomography (PAUSAT) and photothermal infrared microscopy

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