Quantitative Phase Imaging and Artificial Intelligence

Hosted By: Molecular Probes and Nanobio-optics Technical Group

15 September 2022, 10:00 - 11:00 - Eastern Time (US & Canada) (UTC - 05:00)

Quantitative phase imaging (QPI) uses refractive indexes (RIs) as intrinsic imaging contrasts for label-free imaging. Optical diffraction tomography (ODT), also known as holotomography (HT), is one of the 3D QPI techniques. ODT is optical analogous to X-ray computed tomography; multiple 2D holograms of a sample are measured with various illumination angles, from which a 3D RI distribution of the sample is reconstructed by inversely solving the wave equation.

When the label-free and quantitative 3D imaging capability of ODT are combined with machine learning approaches, it can provide synergistic capability in bioimaging and clinical diagnosis. In this webinar hosted by the Molecular Probes and Nanobio-Optics Technical Group, Dr. YongKeun (Paul) Park from KAIST will discuss the potentials and challenges of combining QPI and artificial intelligence in terms of various aspects of imaging and analysis, including segmentation, classification, and imaging inference.

Subject Matter Level: Introductory - Assumes little previous knowledge of the topic

What You Will Learn:

  • The principle of QPI
  • The benefits and limitations of using QPI
  • Applications of QPI with an emphasis on using machine learning approaches

Who Should Attend:

  • Young researchers in optics and photonics who would like to learn about QPI
  • Cell biologists or biophysicists who would like to know potential applications of QPI

About the Presenter: YongKeun (Paul) Park, KAIST

YongKeun (Paul) Park is Endowed Chair Professor of Physics at KAIST. Park earned a Ph.D. in Medical Science and Medical Engineering from Harvard-MIT Health Science and Technology. Dr. Park’s area of research is optics, holography, and biophysics. He has published +160 peer-reviewed papers with +12K citations, including 4 Nat Photon, 1 Nat Mat, 1 Nat Cell Biol, 4 Nat Comm, 4 PRL, 6 PNAS papers. Park is a Fellow of Optica (formerly known as OSA) and Society of Photo-Optical Instrumentation Engineers (SPIE). He received Medals of Honor in Science and Technology (President of South Korea) and JinkiHong Creative Award. Two start-up companies with +80 employees have been created from his research (Tomocube, The.Wave.Talk). To learn more about Prof. Park's research projects, visit his website: