Irene Georgakoudi
Events
Irene Georgakoudi
Thayer School of Engineering, Dartmouth College
Harnessing Label-Free Two-Photon Microscopy for Dynamic Imaging of Cellular Metabolism and Matrix Remodeling in Living Tissues
Label-free two-photon microscopy leveraging endogenous fluorescence and second harmonic generation enables dynamic assessment of cellular metabolism, extracellular matrix remodeling, cell-cell and cell-matrix interactions. This information is critical for advancing diagnostics, therapeutic monitoring, and understanding of disease progression, especially when informed by complementary tools, such as transcriptomics.
About the Speaker
Irene Georgakoudi is a Professor at the Thayer School of Engineering at Dartmouth College and co-director of the Translational Engineering in Cancer program at the Dartmouth Cancer Center. She studied Physics at Dartmouth, Biophysics at the University of Rochester and was introduced to label-free, optical diagnostics at MIT. She continued to pursue this line of research as an independent investigator at Tufts University, after being an Instructor at the Massachusetts General Hospital/Harvard Medical School. Her work focuses on the development and application of imaging modalities that exploit endogenous light scattering and fluorescence contrast to characterize quantitatively tissue function and morphology to improve understanding, diagnosis and monitoring of human diseases. She is a fellow of the American Institute for Biomedical Engineering, Optica and SPIE.
