Application of optical spectroscopy and imaging systems to the study of the brain in both health and disease (i.e., Alzheimer’s, stroke, epilepsy, etc.)
Models of brain disease and optical tools
Photothrombosis
Optical therapeutics
Photodynamic therapy
Advanced High Speed, Volumetric and Large Field-of-view Optical Imaging and Manipulation
Light sheet microscopy
Point spread function engineering and light sculpting (Temporal Focusing, Bessel, structured illumination Airy, etc.)
Volumetric and large-scale imaging
Optical tools for high precision optogenetic manipulation
Voltage imaging
High Resolution Structural Techniques
Fluorophore design and optimization
Clearing techniques and structural imaging, animal to human
Applications of super-resolution
Particle tracking
uCT and electron microscopy
Connectomics
Other emerging structural and connectivity inference technologies
Neuronal Data and Brain Network Analysis Tools
Hybrid theoretical-experimental approaches to network analysis
Tools for large-scale neuronal data extraction data analysis and dimensionality reduction
Models of neuronal network dynamics
Deciphering functions from activity data
Applications of machine learning in neuronal data and networks
Optical data management
Molecular and Genetic Tools for Capturing and Controlling Brain Function
Optode and electrode hardware for excitation and/or recording
Genetically encoded calcium indicators and other molecular sensors
Genetically encodable voltage sensors
Novel forms of functional contrast
New genetic strategies for optogenetics
Modeling and overcoming scatter in optogenetics
Challenges of scaling up optogenetics to non-human primates
Voltage sensitive dyes
Imaging in Scattering Tissue and Deep Tissue Imaging
Adaptive optics strategies
Three- or multiphoton strategies for deep tissue imaging
Hybrid Optical Approaches and Computational Imaging
Photoacoustics / optoacoustics
Acousto-optic approaches
Acoustic modulation of neural activity
Combined optical / PET / CT / MRI
Combined electrical / optical
Computational imaging, light field microscopy and non-imaging forming optical systems
