Optical Molecular Probes, Imaging and Drug Delivery

Optical Molecular Probes, Imaging and Drug Delivery

1. Imaging and Sensing of Biomolecular Processes and Pathways
   • Macroscopic optical/tomographic imaging
   • Advanced microscopy techniques (multiphoton, SHG, FRET, FLIM, SRS, pump-probe, CARS, SWIR, etc.)
   • Photo/opto-acoustics, diffuse reflectance imaging
   • Quantitative phase imaging
   • Vibrational imaging
2. Reporters and Contrast Agents
   • Luminescence and bioluminescence imaging
   • Endogenous contrast
   • Genetically encodable probes
   • Fluorescent molecular probes
   • Nanoparticle probes
3. Advanced Optical Molecular Imaging Instrumentation and Methods
   • Assays
   • Pre-clinical
   • Clinical prototypes (in-vivo/intra-cavital)
   • Surgical microscopes
4. Novel Tools and Approaches for Image Data Analysis and Reconstruction
5. Optical Imaging and Monitoring of Drug Delivery
   • Specific delivery and localization
   • Action of drugs
   • Contrast agents
   • Dosimetry in photodynamic, radio and chemotherapies
6. Fluorescent Phantoms and Quantitative Validation Methods
7. Multi-Modal Molecular Imaging Techniques
   • Combinations of optics with MRI, X-ray, radioligands, ultrasound, etc.
   • Multi-scale optical imaging
   • FILM, FRET, OCT, Raman and CARS
8. Pre-Clinical Applications of Optical Molecular Imaging and Spectroscopy
9. Clinical Translation of Optical Molecular Imaging, Spectroscopy and Image Guide Surgery and Therapy