Clinical and Translational Biophotonics

Clinical and Translational Biophotonics (Translational)

1. Preclinical Disease Research: Techniques and Applications
   • Molecular contrast agents, probes and reporters
   • Diffuse optical spectroscopy and imaging methods for small animal models of cancer and other diseases
   • Optical imaging of the cancer microenvironment, processes and pathways
   • Targeted molecular imaging of cancer and quantitative validation methods
   • Bioluminescence techniques and applications to disease research
   • Photoacoustics in disease research
   • Intravital and multiphoton microscopy for pre-clinical disease research
2. Intravital Microscopy for Clinical Applications 
   • OCT techniques and applications in humans
   • Endomicroscopy
   • FLIM for clinical applications
   • Multimodal microscopy for clinical applications
   • Raman microscopy and endoscopy for clinical applications
   • Micro-elastography and optical biomechanics
   • Skin imaging techniques and applications
2. Clinical Spectroscopy 
   • Optical properties of disease
   • Intravital spectroscopy for clinical applications
   • Hyperspectral imaging techniques and applications in medicine
   • Modeling of light propagation and optical properties
3. Intrasurgical Imaging 
   • Optical approaches for surgical guidance
   • Intravital optical biopsy
   • Perfusion evaluation
   • Combined contrast agent / imaging approaches
   • Dynamic contrast
   • Digital staining microscopy
   • Applications in neurological surgery
   • Applications in cancer resection
4. Non-invasive Optical Imaging for Disease Applications 
   • Tomography approaches for clinical applications
   • Multi-modal imaging (e.g., combined with x-ray, MRI, ultrasound)
   • Photoacoustic techniques and applications in the clinic
5. Optical Therapeutics / Theranostics 
   • PDT, agents, techniques and applications
   • Thermal ablation
   • Agents for optical therapy
   • Laser surgery
   • Optical dosimetry
6. Clinical Translation: Biophotonics in the Clinic and Beyond 
   • Global health
   • Applications in women’s health
   • Applications in ophthalmology
   • Applications in dermatology
   • New contrast agents in the clinic
   • Testing and evaluation of new clinical modalities
   • Challenges and trajectories of clinical translation